Síntese em fase sólida convergente de derivados 5-amidos diidropirimidinonas

dc.contributorEifler-Lima, Vera Lucia
dc.creatorSiqueira, Felipe Segabinazzi
dc.creatorCrestani, Allan
dc.creatorCanto, Rômulo Faria Santos
dc.date2010-11-23T04:19:31Z
dc.date2010
dc.identifierhttp://hdl.handle.net/10183/26837
dc.identifier000758698
dc.descriptionDihydropirimidinones (DHPMs) are molecules whose synthesis is known since 1893, and lately has been receiving increased attention due to its diversity of pharmacological actions, such as: anti-tumor activity, antiviral, antiinflammatory, calcium channel blocker and antiparasitic. In our study, we performed the synthesis of DHPM, its hydrolysis by conventional heating and microwave, and after that, was added amine in these DHPMs hydrolysed by solid-phase organic synthesis (SPOS).
dc.formatapplication/pdf
dc.languagepor
dc.rightsOpen Access
dc.subjectSíntese orgânica em fase sólida
dc.subjectDihydropirimidinones
dc.subjectBiginelli reaction
dc.subjectSolid-phase organic synthesis
dc.titleSíntese em fase sólida convergente de derivados 5-amidos diidropirimidinonas
dc.typeTrabalho de conclusão de graduação


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