A new species of Cyrtochilum from the Eastern Cordillera of Colombia is described and illustrated. The new species is most similar to the pink-flowered Cyrtochilum distans but is distinguished by its white and yellow-green flowers with spreading sepals and a pink lip with a basally yellow and apically white callus consisting of two parallel keels (vs. pink lateral sepals that are fused to about half or more of their length and a white callus consisting of two basal and two apical spreading keels).A new species of Cyrtochilum from the Eastern Cordillera of Colombia is described and illustrated. The new species is most similar to the pink-flowered Cyrtochilum distans but is distinguished by its white and yellow-green flowers with spreading sepals and a pink lip with a basally yellow and apically white callus consisting of two parallel keels (vs. pink lateral sepals that are fused to about half or more of their length and a white callus consisting of two basal and two apical spreading keels).