The use of Bulk-Fill composite resins to perform posterior restorations has been massified in recent years in the different clinical disciplines of Dentistry.  This may be due mainly to the simplicity in the application technique of this material as it requires its insertion into the cavity preparation in 4-5mm of composite resin thickness, achieving a considerable reduction of clinical working time. Given the existence of different viscosities of this type of composite resins, certain difficulties have been identified before the selection of each Bulk-Fill material related to the possible combinations that can be made between the different brands available in the market, even when they are used with conventional composite resins. The purpose of the following case report, is to present two step-by-step clinical possibilities using initially, compactable Bulk-Fill composite resin in a single increment for the restoration of a second upper molar, and later, through the combination of Bulk-Fill flowable composite resin together with compactable Bulk-Fill composite resin and a high-refractive-index enamel-like conventional composite resin, for a first upper molar.