Comparative physiological studies on four species of hemofiagellates in culture. III. Effect of the Krebs' cycles intermediates on the respiration
Comparative physiological studies on four species of hemofiagellates in culture. III. Effect of the Krebs' cycles intermediates on the respiration
| dc.creator | Zeledón, Rodrigo | |
| dc.date | 1960-07-01 | |
| dc.date.accessioned | 2023-08-03T18:22:50Z | |
| dc.date.available | 2023-08-03T18:22:50Z | |
| dc.identifier | https://revistas.ucr.ac.cr/index.php/rbt/article/view/30040 | |
| dc.identifier | 10.15517/rev.biol.trop.1960.30040 | |
| dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/7900659 | |
| dc.description | The effect of the Krebs' cycle intermediates upon respiration of the culture forms of Endotrypanum schaudinni, Leishmania enriettii, Schizotrypanum vespertilionis and S. cruzi was examined at two different hydrogen ion concentrations. At pH 7.2, low stimulations with some of the intermediates were observed. At pH 5.0 the stimulations in general were more evident, and alpha ketoglutarate, malate, and pyruvate were oxidized by E. schaudinni at the same rate as glucose while succinate produced a respiratory stimulation 35 per cent higher than that of glucose. A t the same low pH, the other three species were able to utilize some pyruvate, whereas acetate inhibited all of them. The increase in respiration produced by the tricarboxylic acids was almost negligible, regardless of the pH, and in some instances the substances rather had a depressive action on the respiration. It is believed that the tricarboxylic acid cycle is present in the four species and the possibility of its importance in roles other than energy production, in Leishmania and Schizotrypanum, is discussed. | en-US |
| dc.description | Se estudia el efecto de las sustancias intermediarías del ciclo de Krebs en la respiración de las formas de cultivo de Endotrypanum schaudinni, Leishmania enriettii, Schizotrypanum vespertilionis y S. cruzi, a dos diferentes con centraciones de iones de hidrógeno. A pH 7.2 se observaron estímulos pequeños; a pH 5.0 los estímulos respiratorios fueron más evidentes y en el caso de E. schalldinni, alfa-cetoglutarato, malato y piruvato fueron oxidados con la misma intensidad que glucosa y el succinato produjo un estímulo respiratorio 35 por ciento más elevado que el producido por el carbohidrato. Al mismo pH ácido, las otras tres especies fueron capaces de utilizar piruvato, mientras que el acetato fue inhibitorio para todas. Los ácidos tricarboxílicos produjeron un aumento insignificante a cualquiera de los dos pH y en algunos casos hubo un efecto depresivo sobre la respiración. Se concluye que el ciclo de Krebs existe en las cuatro especies y se discute la posibilidad de que el mismo tenga importancia en otros aspectos metabólicos, que no sean la producción de energía, en el caso de Leishmallia y Schizotrypanum. | es-ES |
| dc.format | application/pdf | |
| dc.language | eng | |
| dc.publisher | Universidad de Costa Rica | en-US |
| dc.relation | https://revistas.ucr.ac.cr/index.php/rbt/article/view/30040/30085 | |
| dc.rights | Derechos de autor 1960 Revista de Biología Tropical | es-ES |
| dc.source | Revista de Biología Tropical; Vol. 8 No. 1 (1960): Volume 8 - Regular number 1 - July 1960; 25–33 | en-US |
| dc.source | Revista de Biología Tropical; Vol. 8 Núm. 1 (1960): Volumen 8 - Número regular 1 - Julio 1960; 25–33 | es-ES |
| dc.source | Revista Biología Tropical; Vol. 8 N.º 1 (1960): Volumen 8 - Número regular 1 - Julio 1960; 25–33 | pt-PT |
| dc.source | 2215-2075 | |
| dc.source | 0034-7744 | |
| dc.source | 10.15517/rbt.v8i1 | |
| dc.title | Comparative physiological studies on four species of hemofiagellates in culture. III. Effect of the Krebs' cycles intermediates on the respiration | en-US |
| dc.title | Comparative physiological studies on four species of hemofiagellates in culture. III. Effect of the Krebs' cycles intermediates on the respiration | es-ES |
| dc.type | info:eu-repo/semantics/article | |
| dc.type | info:eu-repo/semantics/publishedVersion | |
| dc.type | Article | en-US |