Identification of CD4 + T cell epitopes of Taenia solium paramyosin.

dc.creatorHECTOR SAMUEL LOPEZ MORENO
dc.creatorMARIA DOLORES CORREA BELTRAN
dc.creatorJUAN PEDRO LACLETTE SN ROMAN
dc.creatorVIANNEY FRANCISCO ORTIZ NAVARRETE
dc.date2003
dc.date.accessioned2023-07-25T16:15:46Z
dc.date.available2023-07-25T16:15:46Z
dc.identifier10.1111/j.1365-3024.2003.00658.x
dc.identifierhttp://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/3111
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/7805152
dc.descriptionT cell mediated response is involved in a protective immune response against experimental cysticercosis conferred by immunization with Taenia solium paramyosin (TPmy) to BALB/c mice. In this study, we analysed the TPmy amino acid sequence for predicted CD4+ T cells epitopes. Five different regions of this protein showed that the residues anchor to bind the I-A d molecule; synthetic peptides containing these epitopes were evaluated for their ability to induce lymphoproliferative responses of spleen cells from TPmy immunized mice. Among them, Tp176 (amino acids 176-192 sequence DDLQRQMADANSAKSRL) was the immunodominant T cell epitope of TPmy. Delineation of this epitope should facilitate analysis of the role of CD4+ T cell response in experimental cysticercosis.
dc.formatapplication/pdf
dc.languageeng
dc.publisherWiley
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/4.0
dc.sourceParasite Immunology 25(10):513 - 516
dc.subjectinfo:eu-repo/classification/cti/3
dc.subjectLinfocitos T CD4-Positivos - Inmunología
dc.subjectCisticercosis - Inmunología
dc.subjectEpítopos de Linfocito T - Química
dc.subjectTaenia solium - Inmunología
dc.subjectTropomiosina - Inmunología
dc.subjectCD4-Positive T - Lymphocytes - Immunology
dc.subjectCysticercosis - Immunology
dc.subjectEpitopes, T - Lymphocyte - Chemistry
dc.subjectTaenia solium - Immunology
dc.subjectTropomyosin - Immunology
dc.subjectTaenia solium paramiosina
dc.subjectEpítopo de célula T CD4 +
dc.subjectCisticercosis
dc.subjectI-Ad
dc.subjectTaenia solium paramyosin
dc.subjectCD4+ T cell epitope
dc.subjectCysticercosis
dc.titleIdentification of CD4 + T cell epitopes of Taenia solium paramyosin.
dc.typeinfo:eu-repo/semantics/article


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