Article
High expression of prolactin receptor is associated with cell survival in cervical cancer cells.
Registro en:
Lopez-Pulido, E. I., Muñoz-Valle, J. F., Del Toro-Arreola, S., Jave-Suárez, L. F., Bueno-Topete, M. R., Estrada-Chávez, C., & Pereira-Suárez, A. L. (2013). High expression of prolactin receptor is associated with cell survival in cervical cancer cells. Cancer Cell International, 13(1), 103. doi:10.1186/1475-2867-13-103
1475-2867
Autor
López Pulido, Edgar Iván
Del Toro Arreola, Susana
Estrada Chávez, Ciro
Muñoz Valle, José Francisco
Jave Suárez, Luis F.
Bueno Topete, Miriam R.
Pereira Suárez, Ana Laura
Institución
Resumen
The altered expression of prolactin (PRL) and its receptor (PRLR) has been implicated in breast and other types of cancer. There are few studies that have focused on the analysis of PRL/PRLR in cervical cancer where the development of neoplastic lesions is influenced by the variation of the hormonal status. The aim of this study was to evaluate the expression of PRL/PRLR and the effect of PRL treatment on cell proliferation and apoptosis in cervical cancer cell lines.