Poly(methyl methacrylate)/calcium oxide (PMMA/CaO) composite in the form of solution, has been successful prepared for its application as coating on ultra high molecular weight polyethylene (UHMWPE). The hybrid coating was prepared by mixing the CaO powder in situ with PMMA polymerization from its monomer methyl methacrylate (MMA) using benzoyl peroxide (BPO) as initiator and toluene as solvent. The FTIR technique was used to study the hybrid composite coatings. Coating surface morphology was characterized by Scanning Electron Microscopy founding out CaO particles on the polymer surface; by image analysis was found that the incorporation of CaO powder increases the PMMA/CaO coating thickness obtaining a mean value of 107.57 μm. Wear test of PMMA/CaO coatings on UHMWPE were carried out on a pin-on-disk tribometer in dry conditions with a normal load of 5 N against stainless steel.