Capsicum annuum var. aviculare is one of the most extremely hot chilies, measuring between 50,000 and 100,000 Scoville Units. In the present work we studied the growth and development of chiltepin (Mazocahui), under field conditions, inoculated with previously selected and cultivated native strains of Bacillus amyloliquefaciens and Azospirillum halopraeferens. The seed was inoculated by the vacuum technique, and later at 34, 120, 180 and 210 days after germination. A drip irrigation system with a salinity (TDS) = 0.8 ppt was used. The results show that germination is significantly favored by the promoter effect caused by the beneficial bacteria. These inoculants increased some parameters of growth and development. We found significant differences regarding the control for the total weight and length of root and stem of the plants, as well as the total content of proteins, and in some parts of the plant analyzed as stem and leaf. Both bacteria increased fruit yield in the Mazocahui genotype. Our findings suggest that the application of strains of Bacillus amyloliquefaciens and Azospirillum halopraeferens, influence the increase in yield of Capsicum annuum var. aviculare, under field conditions. In addition, the data show the usefulness of the inoculation of chiltepin seed for agricultural producers in semi-arid areas where salinity is a problem.