Identification of novel genomic regions and superior alleles associated with zn accumulation in wheat using a genome-wide association analysis method

dc.creatorZhengfu Zhou
dc.creatorXia Shi
dc.creatorGanqing Zhao
dc.creatorMaomao Qin
dc.creatorIbba, M.I.
dc.creatorYahuan Wang
dc.creatorWenxu Li
dc.creatorPan Yang
dc.creatorZhengqing Wu
dc.creatorZhensheng Lei
dc.creatorJiansheng Wang
dc.date2021-01-13T01:20:14Z
dc.date2021-01-13T01:20:14Z
dc.date2020
dc.date.accessioned2023-07-17T20:06:38Z
dc.date.available2023-07-17T20:06:38Z
dc.identifierhttps://hdl.handle.net/10883/21109
dc.identifier10.3390/ijms21061928
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/7512895
dc.descriptionMicronutrient deficiencies, and especially zinc (Zn) deficiency, pose serious health problems to people who mainly depend on cereal-based diets. Here, we performed a genome-wide association study (GWAS) to detect the genetic basis of the Zn accumulation in wheat (Triticum aestivum L.) grains with a diversity panel of 207 bread wheat varieties. To uncover authentic quantitative trait loci (QTL) controlling Zn accumulation, the varieties were planted in three locations. In total, 29 unique loci associated with Zn grain accumulation were identified. Notably, seven non-redundant loci located on chromosomes 1B, 3B, 3D, 4A, 5A, 5B, and 7A, were detected at least in two environments. Of these quantitative trait loci (QTL), six coincided with known QTL or genes, whereas the highest effect QTL on chromosome 3D identified in this study was not reported previously. Searches of public databases revealed that the seven identified QTL coincided with seven putative candidate genes linked to Zn accumulation. Among these seven genes, NAC domain-containing protein gene (TraesCS3D02G078500) linked with the most significant single nucleotide polymorphism (SNP) AX-94729264 on chromosome 3D was relevant to metal accumulation in wheat grains. Results of this study provide new insights into the genetic architecture of Zn accumulation in wheat grains.
dc.languageEnglish
dc.publisherMDPI
dc.relationhttps://www.mdpi.com/1422-0067/21/6/1928#supplementary
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dc.rightsOpen Access
dc.source6
dc.source21
dc.source1661-6596
dc.sourceInternational Journal of Molecular Sciences
dc.source1928
dc.subjectAGRICULTURAL SCIENCES AND BIOTECHNOLOGY
dc.subjectZinc Accumulation
dc.subjectGenome-Wide Association Study
dc.subjectGenetic Loci
dc.subjectSuperior and Inferior Alleles
dc.subjectWHEAT
dc.subjectZINC
dc.subjectLOCI
dc.subjectALLELES
dc.titleIdentification of novel genomic regions and superior alleles associated with zn accumulation in wheat using a genome-wide association analysis method
dc.typeArticle
dc.typePublished Version
dc.coverageBasel (Switzerland)


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