Articulo
The use of cyclophosphamide as an enhancer of the vaccine against foot-and-mouth disease
Registro en:
issn:0014-4754
issn:1420-9071
issn:1420-682x
Autor
Portiansky, Enrique Leo
González, Pedro Horacio
Laguens, Rubén P.
Institución
Resumen
The immunization of biungulate animals with killed foot-and-mouth disease virus (FMDV) requires periodic vaccinations due to a low vaccine immunogenicity. Therefore, FMDV antigens need to be combined with adjuvants such as aluminum hydroxide, saponin or oil emulsions. Animal handling for periodic inoculations, and the repeated doses of vaccines that have to be administered increase the commercialization costs. Moreover, the use of adjuvants may induce adverse effects. Facultad de Ciencias Veterinarias