dc.creator | Di Ianni, Mauricio Emiliano | |
dc.creator | Talevi, Alan | |
dc.date | 2014-02 | |
dc.date | 2020-08-18T18:42:13Z | |
dc.date.accessioned | 2023-07-14T19:47:42Z | |
dc.date.available | 2023-07-14T19:47:42Z | |
dc.identifier | http://sedici.unlp.edu.ar/handle/10915/102558 | |
dc.identifier | https://ri.conicet.gov.ar/11336/31186 | |
dc.identifier | https://www.smartscitech.com/index.php/MCE/article/view/922 | |
dc.identifier | issn:2330-3883 | |
dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/7436715 | |
dc.description | Network-pharmacology is a field of pharmacology emerging from the observation that most clinical drugs have multiple targets, contrasting with the previously dominant <i>magic bullet</i> paradigm which proposed the search of exquisitely selective drugs. What is more, drug targets are often involved in multiple diseases and frequently present co-expression patterns. Therefore, useful therapeutic information can be drawn from network representations of drug targets. Here, we discuss potential applications of drug-target networks in the field of antiepileptic drug development. | |
dc.description | Facultad de Ciencias Exactas | |
dc.format | application/pdf | |
dc.format | 21-28 | |
dc.language | es | |
dc.rights | http://creativecommons.org/licenses/by-nc-sa/4.0/ | |
dc.rights | Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) | |
dc.subject | Ciencias Exactas | |
dc.subject | Química | |
dc.subject | Biología | |
dc.subject | Drug-protein networks | |
dc.subject | Network analysis | |
dc.subject | Epilepsy | |
dc.subject | Drug repositioning | |
dc.subject | Drug repurposing | |
dc.title | How Can Network-Pharmacology Contribute to Antiepileptic Drug Development? | |
dc.type | Articulo | |
dc.type | Articulo | |