Artículo
1-[2-(4-Nitrophenyl)-5-(5-phenyl-1,2-oxazol-3-yl)-1,2,3, 4-tetrahydroquinolin-4-yl]pyrrolidin-2-one
Fecha
2011-02Autor
Gutierrez, Margarita
Astudillo, Luis
Quesada, Luisa
Brito, Iván
López-Rodríguez, Matías
Institución
Resumen
The title compound, (I) C28H24N4O 4, is the trans diastereoisomer of the compound 1-[2-(4-nitrophenyl)- 6-(5-phenyl-3-isoxazolyl)-1,2,3,4-tetrahydro-4-quinolinyl]-2-pyrrolidinone monohydrate, (II) [Gutierrez et al. (2011). Acta Cryst. E67, o175-o176]. The most obvious differences between the diastereoisomers are the dihedral angles between the isoxazole ring and the benzene and phenyl rings [47.0 (2); 56.4 (2) and 33.3 (2); 11.0 (2)°, respectively, for (II) 75.4 (2) and 5.8 (3), respectively, for (I)]. In the crystal of (I), the molecules are linked by N -H⋯O interactions into a chain along [001] with graphset notation C(8).