ARTÍCULO
Enfermedad de Devic con respuesta favorable a rituximab: reporte de un caso
Fecha
2019Autor
Berrezueta Córdova, Diana Lucila
Pacurucu Jara, Mónica Elizabeth
Encalada García, Carlos Eduardo
Calle Samaniego, Edison Damián
Orellana Cobos, Danilo Fernando
Institución
Resumen
Devic’s disease, is also called neuromyelitis optica, it is a demyelinating autoimmune entity of the central nervous system, it is uncommon and it compromises the optic nerves and the spinal cord, causing loss of visual acuity and motor impairment. A clinical case of a 25-year-old woman with signs of sudden myelopathy and amaurosis is presented. It is fulfilling crite-ria for neuromyelitis optica. The treatment with methylprednisolone boluses started without any improvement, and Rituximab was applied with an early favorable response. Rituximab belongs to the group of anti-CD20 monoclo-nal antibodies, it was an important option in the absence of response to the first line of treatment.