Article
Selective digestive decontamination with oral colistin plus gentamicin for persistent bacteraemia caused by non-carbapenemase-producing carbapenem-resistant Klebsiella pneumoniae in a neutropenic patient
Fecha
2021Registro en:
Autor
Spencer-Sandino, Maria
Riquelme-Neira, Roberto
Shropshire, William C.
Dinh, An Q.
González-Rocha, Gerardo
González-Muñoz, Paulina
Vera-Leiva, Alejandra
Araos, Rafael
Hanson, Blake
Arias, Cesar A
Munita, José
Institución
Resumen
Carbapenem-resistant Klebsiella pneumoniae (CRKp) have become an increasing public health problem worldwide. While most CRKp around the world harbour a carbapenemase enzyme, the clinical relevance of non-carbapenemase-producing CRKp (non-CP-CRKp) is increasingly recognized. Selective digestive decontamination (SDD) has been proven successful as a decolonization strategy for patients colonized with Gram-negatives in the ICU. However, it is not regularly used to treat invasive infections.