This editorial briefly explores some of the distinctions between drugs and pharmaceuticals, alongside definitions regarding Cannabis sativa and its use in the context of a newly legal industry. Furthermore, medical cannabis is considered with regard to its toxicity, its social uses, its pharmacological activity, its legal paradoxes, and the scientific revolution sparked by the study of the endocannabinoid system, which has gained a great deal of relevance for modern physiology and pharmacology.En este editorial, se propone un breve recorrido por algunas distinciones entre drogas y fármacos y definiciones sobre Cannabis sativa y su uso en una nueva industria legal. Por otro lado, se aborda la toxicidad del cannabis medicinal, sus usos sociales, la acción farmacológica, las paradojas legales, y la revolución científica que ha generado el estudio del sistema endocannabinoide y que ha sido de gran relevancia para la fisiología y la farmacología moderna.