Otros
Update on Melasma-Part II: Treatment
Fecha
2022-07-29Registro en:
Dermatology And Therapy. Northcote: Adis Int Ltd, v. 12, n. 9, p. 1989-2012, 2022.
2193-8210
10.1007/s13555-022-00780-4
WOS:000832846100003
Autor
Universidade Federal de São Paulo (UNIFESP)
Universidade Estadual Paulista (UNESP)
Institución
Resumen
Melasma is a prevalent chronic relapsing pigmentary disorder that affects photoexposed areas, especially in women of childbearing age. Although there is currently no curative treatment available for melasma, this manuscript critically reviews the knowledge regarding photoprotection, topical and oral therapies, and procedures such as peelings, laser, and microneedling that represent the main strategies for control and prevention of this disease. As the pathogenesis of melasma is not entirely understood, there are prospects for the development of new therapeutic strategies that might act on the pathways that promote sustained pigmentation rather than merely decreasing melanin synthesis and removing melanin from the epidermis.