Crystal structure of bucain, a three-fingered toxin from the venom of the Malayan krait (Bungarus candidus)

Artículos de revistas

Fecha

2009-12-01

Registro en:

Protein and Peptide Letters, v. 16, n. 12, p. 1473-1477, 2009.

0929-8665

http://hdl.handle.net/11449/225725

10.2174/092986609789839304

2-s2.0-73449108823

https://repositorioslatinoamericanos.uchile.cl/handle/2250/5405855

Autor

Universidade Estadual Paulista (UNESP)

National University of Singapore

Virginia Commonwealth University

Butantan Institute

Brazilian Synchrotron Light Laboratory

Institución

Universidade Estadual Paulista (Brasil)

Resumen

Bucain, a potent neurotoxin isolated from the venom of the Malayan krait (Bungarus candidus), induces paralysis and death. Its crystal structure has been determined at 2.10 Å resolution and based on the molecular topology and hydrophobicity profile is structurally classified as a three-fingered a-neurotoxin possessing a positively charged AChR-binding site. © 2009 Bentham Science Publishers Ltd.

Materias

Bucain

Bungarus candidus

Crystal structure

Three-finger α-neurotoxin

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