Long-term effects of imipramine on striatal dopamine autoreceptor function: Involvement of both noradrenergic and serotonergic systems

Artículos de revistas

Fecha

1992-01-01

Registro en:

General Pharmacology, v. 23, n. 3, p. 397-401, 1992.

0306-3623

http://hdl.handle.net/11449/219151

10.1016/0306-3623(92)90101-O

2-s2.0-0026598315

https://repositorioslatinoamericanos.uchile.cl/handle/2250/5399280

Autor

Universidade de São Paulo (USP)

Universidade Estadual Paulista (UNESP)

Institución

Universidade Estadual Paulista (Brasil)

Resumen

1. 1. The effects of apomorphine (APO) administration on DA system activity were assessed by measuring dopamine metabolite levels (HVA) in several circumstances. 2. 2. Pretreatment with IMI reduced the effect of APO on HVA levels. 3. 3. Pretreatments with either IDE or DMI did not reduce the effect of APO on HVA levels. 4. 4. Reductions of either NE and 5-HT levels after DSP4 and pCPA restored the effect of APO after IMI pretreatment. © 1992.

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