Artículos de revistas
Losartan improves alveolar bone dynamics in normotensive rats but not in hypertensive rats
Fecha
2019-10-07Registro en:
Journal of Applied Oral Science. Faculdade De Odontologia De Bauru - USP, v. 27, p. -, 2019.
1678-7757
1678-7765
10.1590/1678-7757-2018-0574
S1678-77572019000100479
S1678-77572019000100479.pdf
Autor
Universidade Estadual Paulista (Unesp)
Institución
Resumen
Hypertension is one of the main causes of premature death in the world; also, it is associated with several bone alterations. Preclinical studies have demonstrated delayed alveolar bone healing in hypertensive rats. However, losartan has been favorable for consolidation of bone grafts and reduction in active periodontitis. Therefore, losartan is suggested to be effective in bone formation stages, as well as in the synthesis of matrix proteins and mineralization.