Otros
Application of MIL-100(Fe) in drug delivery and biomedicine
Fecha
2021-02-01Registro en:
Journal of Drug Delivery Science and Technology, v. 61.
1773-2247
10.1016/j.jddst.2020.102217
2-s2.0-85096474114
8534138813417161
0000-0003-1574-681X
Autor
Universidade Estadual Paulista (Unesp)
Institución
Resumen
Metal-organic frameworks (MOFs) are an interesting and advantageous class of coordination polymers, constructed from metal ion/clusters and organic linkers. They have attracted growing research interest over the past decades and captured attention in the field of biomedical applications due to their high drug loading capacity, post-synthetic modification, and the ability to synthesize at the nanoscale size. In particular, MIL-100(Fe) is a mesoporous, environmentally friendly, and water-stable material. This review summarizes and discusses the recent advances in the synthesis of the micro and nano-MIL-100(Fe), the physicochemical stability concerning changes in pH, temperature, and physiological conditions, as well as biomedical applications such as biosensors, phototherapy, encapsulation methods, and drug release. Finally, future challenges and perspectives in this field are presented.