Mathematical model of an antiretroviral therapy to HIV via Filippov theory

Artículos de revistas

Fecha

2020-12-15

Registro en:

Applied Mathematics and Computation, v. 387.

0096-3003

http://hdl.handle.net/11449/198651

10.1016/j.amc.2020.125179

2-s2.0-85081937204

https://repositorioslatinoamericanos.uchile.cl/handle/2250/5379285

Autor

Universidade Estadual Paulista (Unesp)

Universidade de São Paulo (USP)

Institución

Universidade Estadual Paulista (Brasil)

Resumen

This work aims to study some qualitative features of piecewise smooth systems applied to the dynamics of the Human Immunodeficiency Virus (HIV). The application of sliding mode control and strategies of structured treatment interruptions in HIV is a new and challenging research area, which deserves attention and improvement. We investigate the dynamic behavior of the discontinuous mathematical model and we observe the occurrence of typical singularities.

Materias

Antiretroviral therapies

HIV

Intermittent treatment

Piecewise smooth vector fields

Typical singularities

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