Otros
Controlling proteolysis of Clp peptidase: a possible target for combating mitochondrial diseases
Fecha
2019-05-01Registro en:
International Journal of Biochemistry and Cell Biology, v. 110, p. 140-142.
1878-5875
1357-2725
10.1016/j.biocel.2019.03.007
2-s2.0-85062893393
Autor
Universidade Estadual Paulista (Unesp)
Institución
Resumen
Some mechanisms of cellular stress, aging, and apoptosis are related to proteolysis. With respect to ClpP, little is known about the mechanical manner in which the substrate is hydrolyzed in and released from the degradation chamber. Furthermore, what would be the real influence of ClpP in mammalian UPR mt ?