| dc.creator | Puerto Galvis, Carlos Eduardo | |
| dc.creator | Vargas Méndez, Leonor Yamile | |
| dc.creator | Kouznetsov, Vladimir V. | |
| dc.date | 2019-03-31T22:49:58Z | |
| dc.date | 2019-03-31T22:49:58Z | |
| dc.date | 2013 | |
| dc.date | info:eu-repo/date/embargoEnd/2024-01-31 | |
| dc.date.accessioned | 2022-12-07T14:47:32Z | |
| dc.date.available | 2022-12-07T14:47:32Z | |
| dc.identifier | http://repositorio.colciencias.gov.co/handle/11146/34156 | |
| dc.identifier | Contiene 108 referencias bibliográficas. Véase documento adjunto | |
| dc.identifier | 10.1111/cbdd.12180 | |
| dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/5301329 | |
| dc.description | Chemical and pharmacological information on cantharidin-based small molecules was analyzed. The review summarizes new facts about blister beetles’ metabolites for the period 2006–2012. General synthetic approaches to cantharidin-based small molecules as well as their chemical transformations and biological activities related to cantharidin, norcantharidin, cantharidimide, and norcantharimide analogs, especially their inhibitory activity of phosphoprotein phosphatases in cancer treatment, were discussed in this mini review, which could help to design new small molecule modulators for other biological models. | |
| dc.description | Departamento Administrativo de Ciencia, Tecnología e Innovación [CO] Colciencias | |
| dc.description | 5507-543-31904 | |
| dc.description | Programa: Bioprospección y desarrollo de ingredientes naturales para las industrias cosmética, farmacéutica y de productos de aseo con base en la biodiversidad colombiana | |
| dc.description | no | |
| dc.format | pdf | |
| dc.format | 23 páginas | |
| dc.format | application/pdf | |
| dc.language | eng | |
| dc.relation | Programa: Bioprospección y desarrollo de ingredientes naturales para las industrias cosmética, farmacéutica y de productos de aseo con base en la biodiversidad colombiana. La publicación completa está disponible en : <a href="http://repositorio.colciencias.gov.co/handle/11146/34163" target="blank">http://repositorio.colciencias.gov.co/handle/11146/34163</a> | |
| dc.rights | info:eu-repo/semantics/embargoedAccess | |
| dc.source | Chem Biol Drug Des 2013; 82: 477–499 | |
| dc.subject | Productos farmacéuticos | |
| dc.subject | Anticancer activity | |
| dc.subject | Blister beetles | |
| dc.subject | Cantharidin analogs | |
| dc.subject | Diels–Alder cycloaddition reactions | |
| dc.subject | Drug design and development | |
| dc.subject | Protein phosphatases inhibitory activity | |
| dc.subject | Bioquímica vegetal | |
| dc.subject | Aceites esenciales | |
| dc.subject | Aceites combustibles | |
| dc.subject | Aceites vegetales | |
| dc.subject | Biotecnología | |
| dc.subject | Química agrícola | |
| dc.title | Cantharidin-Based Small Molecules as Potential Therapeutic Agents | |
| dc.type | info:eu-repo/semantics/article | |
| dc.type | info:eu-repo/semantics/publishedVersion | |
| dc.coverage | Colombia | |
