3-Arylcoumarins as highly potent and selective monoamine oxidase B inhibitors: Which chemical features matter?

dc.creatorMellado M.
dc.creatorMella J.
dc.creatorGonzález C.
dc.creatorViña D.
dc.creatorUriarte E.
dc.creatorMatos M.J.
dc.date.accessioned2020-09-02T22:22:53Z
dc.date.accessioned2022-11-08T20:24:38Z
dc.date.available2020-09-02T22:22:53Z
dc.date.available2022-11-08T20:24:38Z
dc.date.created2020-09-02T22:22:53Z
dc.date.issued2020
dc.identifier101, , -
dc.identifier00452068
dc.identifierhttps://hdl.handle.net/20.500.12728/5286
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/5145339
dc.languageen
dc.publisherAcademic Press Inc.
dc.subject3-Arylcoumarins
dc.subject3D-QSAR models
dc.subjectDrug design
dc.subjectMolecular docking
dc.subjectMonoamine oxidase B inhibitors
dc.subject3 ( 2',4' dimethoxyphenyl) 6 methylcoumarin
dc.subject3 ( 3',4' dihydroxyphenyl) 6 methylcoumarin
dc.subject3 ( 3',4' dimethoxyphenyl) 6 methylcoumarin
dc.subject3 ( 3',5' dimethoxyphenyl) 8 methylcoumarin
dc.subject3 ( 5' bromo 2',4' dimethoxyphenyl) 6 methylcoumarin
dc.subject3 arylcoumarin derivative
dc.subject8 ethoxy 3 ( 3',4' dimethoxyphenyl)coumarin
dc.subject8 ethoxy 3 ( 3',4',5' trimethoxyphenyl)coumarin
dc.subject8 methoxy 3 ( 3 tolyl)coumarin
dc.subjectamine oxidase (flavin containing) isoenzyme B
dc.subjectcoumarin derivative
dc.subjectdopamine
dc.subjectmonoamine oxidase B inhibitor
dc.subjectmonoamine oxidase inhibitor
dc.subjectunclassified drug
dc.subjectanimal cell
dc.subjectArticle
dc.subjectbiological activity
dc.subjectcomparative molecular field analysis
dc.subjectcomparative molecular similarity indices analysis
dc.subjectdrug design
dc.subjectdrug potency
dc.subjectdrug selectivity
dc.subjectdrug synthesis
dc.subjectenzyme inhibition
dc.subjectIC50
dc.subjectmolecular docking
dc.subjectnonhuman
dc.subjectParkinson disease
dc.subjectpriority journal
dc.subjectprobability
dc.subjectprotein database
dc.subjectprotein degradation
dc.subjectprotein function
dc.subjectthree dimensional quantitative structure activity relationship
dc.title3-Arylcoumarins as highly potent and selective monoamine oxidase B inhibitors: Which chemical features matter?
dc.typeArticle


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