Artículo
E-Cadherin gene expression in oral cancer : Clinical and prospective data
Fecha
2019Registro en:
1698-6946
Autor
López-Verdín, Sandra
de la Luz Martínez-Fierro, Margarita
Garza-Veloz, Idalia
Zamora-Perez, Ana
Grajeda-Cruz, Jonathan
González-González, Rogelio
Molina-Frechero, Nelly
Arocena, Miguel
Bologna-Molina, Ronell
Institución
Resumen
Low protein expression of E-cadherin in oral squamous cell carcinoma (OSCC) has been associated with clinical and histopathological traits such as metastases, recurrence, low survival and poor tumor differentiation, and it is considered a high-risk marker of malignancy. However, it is still unknown whether low expression of E-cadherin is also present at the mRNA level in OSCC cases. Objective: The aim of this study was to compare E-cadherin mRNA expression in OSCC patients and controls and to correlate the expression with clinical and prospective characteristics.