Background: Coronavirus Disease 2019 (COVID-19) causes a lot of morbidity and mortality. More than three-quarters of hospitalized patients experience complications in the kidneys such as acute kidney injury, proteinuria, hematuria, and electrolyte imbalance. The study addressed to get an overview of the profile of serum electrolyte levels and the severity trend of COVID-19 patients with comorbid Type 2 Diabetes (DM) at Dr. Soetomo Hospital, Surabaya.