Serum adipokine levels in patients with systemic lupus erythematosus

dc.creatorDe Sanctis, Juan B.
dc.creatorZABALETA, MERCEDES
dc.creatorBianco Colmenares, Nicolás E.
dc.creatorRIVAS, LILIANA
dc.creatorGarmendia, Jenny V.
dc.date2015-09-28T22:53:31Z
dc.date2015-09-28T22:53:31Z
dc.date2009
dc.date.accessioned2022-10-28T01:15:14Z
dc.date.available2022-10-28T01:15:14Z
dc.identifier0891-6934
dc.identifierhttp://hdl.handle.net/10872/12119
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4945857
dc.descriptionIn patients with systemic lupus erythematosus (SLE) metabolic alterations are often observed, which may be due to either the disease, the genetic background or the treatment. We studied the serum levels of the adipokines leptin, adiponectin, resistin, visfatin and ghrelin in patients with SLE and controls. Leptin levels were lower and adiponectin, ghrelin and visfatin levels were higher in the patients. No significant differences were encountered for resistin. The values of adipokines were independent of treatment, even after correction for body mass index. Inverse correlations were found among leptin and adiponectin, ghrelin and visfatin. We conclude that adipokines are involved in the metabolic imbalance of patients with SLE.
dc.languageen
dc.publisherAutoimmunity
dc.relationVOL. 42;4
dc.subjectAdipokines
dc.subjectleptin
dc.subjectadiponectin
dc.subjectghrelin
dc.subjectresistin
dc.subjectvisfatin
dc.titleSerum adipokine levels in patients with systemic lupus erythematosus
dc.typeArticle


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