Carcinoma medular de tiroides

Abstract

Thyroid medullary carcinoma (TMC) represents 4% to 8% of all thyroid cancers. It mostly occurs in the fifth decade of life, especially in women. In 1959 Hazard, et al. described TMC as a neoplasia which did not prevent follicular cells. Between 1966 and 1967 Williams suggested that follicular cells derived from C parafollicular cells. The sporadic medullary carcinoma represents 60% to 70% of TMC cases. It is presented as an isolated and unilateral tumor. When it is obvious, the lymphatic dissemination occurs. The hereditary type is presented as a multifocal and bilateral tumor. It is easily observed as part of a multiple endocrine neoplasia syndrome. The genetic study for its classification is the gold standard. This is the reason we present a clinical case and take advantage for a bibliographic revision due to its low incidence, hereditary pattern and its complex management