Immunological studies on BaH1 and BaPI, two hemorrhagic metalloproteinases from the venom of the snake Bothrops asper

dc.creatorRucavado Romero, Alexandra
dc.creatorBorkow, Gadi
dc.creatorOvadia, Michael
dc.creatorGutiérrez, José María
dc.date.accessioned2016-11-11T16:38:23Z
dc.date.accessioned2022-10-20T00:22:36Z
dc.date.available2016-11-11T16:38:23Z
dc.date.available2022-10-20T00:22:36Z
dc.date.created2016-11-11T16:38:23Z
dc.date.issued1995-08
dc.identifierhttp://www.sciencedirect.com/science/article/pii/004101019500039O
dc.identifier0041-0101
dc.identifierhttps://hdl.handle.net/10669/29241
dc.identifier10.1016/0041-0101(95)00039-O
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4532812
dc.description.abstractNo immunological cross-reactivity was observed between BaH1 and BaP1, two hemorrhagic metalloproteinases isolated from B. asper venom, by gel immunodiffusion, Western blotting and neutralization studies. Cross-reactivity was detected with antisera against these toxins in several crotaline and viperine snake venoms by ELISA, whereas no reactivity was observed with either antiserum against the venoms of Bothrops nummifer, Crotalus durissus terrificus, Vipera russelli and several elapid venoms. Antiserum against native BaH1 neutralized hemorrhagic activity of the venoms of B. asper, B. atrox, B. jararaca, Crotalus atrox, C. durissus durissus, Echis carinatus and Trimeresurus flavoviridis, being ineffective against the venoms of Agkistrodon bilineatus and Lachesis muta.
dc.languageen_US
dc.sourceToxicon, Volumen 33, número 8. 1995
dc.subjectAnimals
dc.subjectBothrops
dc.subjectCrotalid Venoms
dc.subjectHemorrhage
dc.subjectImmune Sera
dc.subjectMetalloendopeptidases
dc.subjectSnake venom
dc.titleImmunological studies on BaH1 and BaPI, two hemorrhagic metalloproteinases from the venom of the snake Bothrops asper
dc.typeartículo científico


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