Ponencia
Homology and Pharmacophore Modeling, High Throughput Virtual Screening and Molecular Docking Studies to Iden!fy Poten!al Inhibitors of the Two-pore-Domain Potassium Channel K2P9.1 (TASK-3)
Fecha
2017Institución
Resumen
Two-pore domain potassium channels (K2P) give rise to leak potassium currents, which control the excitability of the
cells. The human genome contains 15 KCNK genes coding for proteins able to form K2P channels subdivided into 6 subfamilies
on the basis of