Ponencia
Understanding the Covalent binding of Clavulanate against beta-lactamases (TEM-1 and KPC-2) with QM/ MM methods.
Fecha
2017Institución
Resumen
β-lactamases are a primary cause of bacterial resistance to β-lactam antibiotics for many important human pathogens
(particularly Gram-negative bacteria) (Hermann, Pradon, Harvey, & Mulholland, 2009). Inhibitors of β-lactamase
have been implemented as a d