Ponencia
Studying the Binding Affinity Determinants of a Derivative Series from Sulbactam and Clavulanate as β-Lactamase Inhibitors
Fecha
2015Institución
Resumen
β-Lactamases are responsible for the hydrolysis of the β-lactam ring on many known antibiotics, thus
conferring resistance to bacteria. The increase in the number of β-lactamases and other resistance
mechanisms, together with the few new antibiotics disco