Phenotype of Aeromonas salmonicida sp. salmonicida cyclic adenosine 3’,5’-monophosphate receptor protein (crp) mutants and its virulence in rainbow trout (Oncorhynchus mykiss)

Abstract

Precise deletion of genes related to virulence can be used as a strategy to produce attenuated bacterial vaccines. Here, we study the deletion of the cyclic-3’,5’-adenosine monophosphate (cAMP) receptor protein (Crp) in Aeromonas salmonicida, the causativ