Rememorando la contribución de Goldstein y Brown al estudio del metabolismo del colesterol : a un cuarto de siglo del Premio Nobel de Medicina

Abstract

In December 1985, the Nobel Prize of Medicine was awarded to Drs. Joseph L. Goldstein and Michael S. Brown for their fundamental scientific work on the regulation of cholesterol metabolism mediated by the low density lipoprotein receptor pathway. This article briefly reviews the academic and research accomplishments of Drs. Brown and Goldstein as a tribute to these physician-scientists for their welldeserved award and enormous contribution to biomedical science worldwide.