info:eu-repo/semantics/article
Melampolides from Argentinean Acanthospermum australe
Fecha
2009-08Registro en:
Sánchez, Marianela; Kramer, Fernando Luis; Bargardi, Severino; Palermo, Jorge Alejandro; Melampolides from Argentinean Acanthospermum australe; Elsevier Science; Phytochemistry Letters; 2; 3; 8-2009; 93-95
1874-3900
CONICET Digital
CONICET
Autor
Sánchez, Marianela
Kramer, Fernando Luis
Bargardi, Severino
Palermo, Jorge Alejandro
Resumen
The investigation of the ethanol extract of Acanthospermum australe, collected in the province of Misiones, Argentina, yielded eight melampolides (1-8) of the acanthospermal type. Two of them, 8β-hydroxy-9α-(2-methylbutyryloxy)-14-oxo-acanthospermolide (3) and 9α-hydroxy-8β-(2-methylbutyryloxy)-14-oxo-acanthospermolide (7) are new compounds. Two other compounds (4 and 8) have been previously reported, and the NMR data of 4 are corrected. Compounds 1, 2, 5 and 6 have not been previously reported, but are probably artifacts formed during extraction. Compounds 3, 6 and 7 showed slight antibiotic activity against Gram-positive bacteria.