info:eu-repo/semantics/article
Advances in drug delivery, gene delivery and therapeutic agents based on dendritic materials
Fecha
2019-08Registro en:
Contin, Mario Daniel; Garcia, Cybele; Dobrecky, Cecilia Beatriz; Lucangioli, Silvia Edith; D'accorso, Norma Beatriz; Advances in drug delivery, gene delivery and therapeutic agents based on dendritic materials; Future Medicine Ltd.; Future Medicinal Chemistry; 11; 14; 8-2019; 1791-1810
1756-8919
1756-8927
CONICET Digital
CONICET
Autor
Contin, Mario Daniel
Garcia, Cybele
Dobrecky, Cecilia Beatriz
Lucangioli, Silvia Edith
D'accorso, Norma Beatriz
Resumen
Dendrimers are synthetic polymers that grow in three dimensions into well-defined structures. Their morphological appearance resembles a number of trees connected by a common point. Dendritic nanoparticles have been studied for a large number of pharmaceutical and biomedical applications including gene and drug delivery, clinical diagnosis and MRI. Despite the application of dendrimers, research is still in its childhood in comparison with liposomes and other nanomaterials. They are now playing a key role in several therapeutic strategies, with dendrimer-based products in clinical trials. The aim of this review is to describe the state-of-the-art of biomedical applications of dendrimers-and dendrimer conjugates-such as drug and gene delivery and antiviral activity.