dc.creator | Jaworski, Juan Pablo | |
dc.creator | Vendrell, Alejandrina | |
dc.creator | Chiavenna, Sebastián Matias | |
dc.date.accessioned | 2019-06-14T18:57:32Z | |
dc.date.accessioned | 2022-10-15T14:35:59Z | |
dc.date.available | 2019-06-14T18:57:32Z | |
dc.date.available | 2022-10-15T14:35:59Z | |
dc.date.created | 2019-06-14T18:57:32Z | |
dc.date.issued | 2017-01 | |
dc.identifier | Jaworski, Juan Pablo; Vendrell, Alejandrina; Chiavenna, Sebastián Matias; Neutralizing monoclonal antibodies to fight HIV-1: On the threshold of success; Frontiers Media S.A.; Frontiers in Immunology; 7; JAN; 1-2017 | |
dc.identifier | 1664-3224 | |
dc.identifier | http://hdl.handle.net/11336/78376 | |
dc.identifier | CONICET Digital | |
dc.identifier | CONICET | |
dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/4397571 | |
dc.description.abstract | Anti-human immunodeficiency virus type-1 (anti-HIV-1) neutralizing monoclonal antibodies are broadening the spectrum of pre- and post-exposure treatment against HIV-1. A better understanding of how these antibodies develop and interact with particular regions of the viral envelope protein is guiding a more rational structure-based immunogen design. The aim of this article is to review the most recent advances in the field, from the development of these particular antibodies during natural HIV-1 infection, to their role preventing infection, boosting endogenous immune responses and clearing both free viral particles and persistently infected cells. | |
dc.language | eng | |
dc.publisher | Frontiers Media S.A. | |
dc.relation | info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225137/ | |
dc.relation | info:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/articles/10.3389/fimmu.2016.00661 | |
dc.relation | info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.3389/fimmu.2016.00661 | |
dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.subject | Human Immunodeficiency Virus | |
dc.subject | Neutralizing Antibodies | |
dc.subject | Prophylaxis | |
dc.subject | Reservoir | |
dc.subject | Treatment | |
dc.subject | Vaccine | |
dc.title | Neutralizing monoclonal antibodies to fight HIV-1: On the threshold of success | |
dc.type | info:eu-repo/semantics/article | |
dc.type | info:ar-repo/semantics/artículo | |
dc.type | info:eu-repo/semantics/publishedVersion | |