info:eu-repo/semantics/article
Amide Bond Formation Catalyzed by Recyclable Copper Nanoparticles Supported on Zeolite Y under Mild Conditions
Fecha
2019-03Registro en:
Moglie, Yanina Fernanda; Buxaderas, Eduardo; Mancini Gonzalez, Agustina Eliana; Alonso, Francisco; Radivoy, Gabriel Eduardo; Amide Bond Formation Catalyzed by Recyclable Copper Nanoparticles Supported on Zeolite Y under Mild Conditions; Wiley VCH Verlag; Chemcatchem; 11; 5; 3-2019; 1487-1494
1867-3880
CONICET Digital
CONICET
Autor
Moglie, Yanina Fernanda
Buxaderas, Eduardo
Mancini Gonzalez, Agustina Eliana
Alonso, Francisco
Radivoy, Gabriel Eduardo
Resumen
A series of catalysts based on supported copper nanoparticles have been prepared and tested in the amide bond formation from tertiary amines and acid anhydrides, in the presence of tert-butyl hydroperoxide as an oxidant. Copper nanoparticles on zeolite Y (CuNPs/ZY) was found to be the most efficient catalyst for the synthesis of amides, working in acetonitrile as solvent, under ligand- and base-free conditions in air. The products were obtained in good to excellent yields and in short reaction times. The CuNPs/ZY system also exhibited higher catalytic activity than some commercially available copper and iron sources and it was reused in ten reaction cycles without any further pre-treatment. This methodology has been successfully scaled-up to a gram scale with no detriment to the yield.