Transcriptional control of a plant stem cell niche

dc.creatorBusch, Wolfang
dc.creatorMiotk, Andrej
dc.creatorAriel, Federico Damian
dc.creatorZhao, Zhong
dc.creatorForner, Joachim
dc.creatorDaum, Gabor
dc.creatorSuzaki, Takuya
dc.creatorSchuster, Christoph
dc.creatorSchultheiss, Sebastian J.
dc.creatorLeibfried, Andrea
dc.creatorHaubeiß, Silke
dc.creatorHa, Nati
dc.creatorChan, Raquel Lia
dc.creatorLohmann, Jan U.
dc.date.accessioned2019-05-09T13:58:13Z
dc.date.accessioned2022-10-15T14:28:08Z
dc.date.available2019-05-09T13:58:13Z
dc.date.available2022-10-15T14:28:08Z
dc.date.created2019-05-09T13:58:13Z
dc.date.issued2010-05
dc.identifierBusch, Wolfang; Miotk, Andrej; Ariel, Federico Damian; Zhao, Zhong; Forner, Joachim; et al.; Transcriptional control of a plant stem cell niche; Cell Press; Developmental Cell; 18; 5; 5-2010; 841-853
dc.identifier1534-5807
dc.identifierhttp://hdl.handle.net/11336/75950
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4396848
dc.description.abstractDespite the independent evolution of multicellularity in plants and animals, the basic organization of their stem cell niches is remarkably similar. Here, we report the genome-wide regulatory potential of WUSCHEL, the key transcription factor for stem cell maintenance in the shoot apical meristem of the reference plant Arabidopsis thaliana. WUSCHEL acts by directly binding to at least two distinct DNA motifs in more than 100 target promoters and preferentially affects the expression of genes with roles in hormone signaling, metabolism, and development. Striking examples are the direct transcriptional repression of CLAVATA1, which is part of a negative feedback regulation of WUSCHEL, and the immediate regulation of transcriptional repressors of the TOPLESS family, which are involved in auxin signaling. Our results shed light on the complex transcriptional programs required for the maintenance of a dynamic and essential stem cell niche.
dc.languageeng
dc.publisherCell Press
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.devcel.2010.03.012
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S1534580710001516
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectWUSCHEL
dc.subjectCLAVATA
dc.subjectTRANSCRIPTOMICS
dc.subjectSHOOT APICAL MERISTEM
dc.titleTranscriptional control of a plant stem cell niche
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


Este ítem pertenece a la siguiente institución