info:eu-repo/semantics/article
Illudalane sesquiterpenoids from the soft coral Alcyonium paessleri: The first natural nitrate esters
Fecha
2000-07Registro en:
Palermo, Jorge Alejandro; Rodriguez Brasco, Maria Florencia; Spagnuolo, Carla Cecilia; Seldes, Alicia M.; Illudalane sesquiterpenoids from the soft coral Alcyonium paessleri: The first natural nitrate esters; American Chemical Society; Journal of Organic Chemistry; 65; 15; 7-2000; 4482-4486
0022-3263
CONICET Digital
CONICET
Autor
Palermo, Jorge Alejandro
Rodriguez Brasco, Maria Florencia
Spagnuolo, Carla Cecilia
Seldes, Alicia M.
Resumen
Fifteen illudalane sesquiterpenoids, alcyopterosins A-O (1-15) have been isolated from the subAntarctic soft coral Alcyonium paessleri which was collected at a depth of 200 m near the South Georgia Islands, and their structures were elucidated by spectroscopic techniques. Eight of these compounds (2, 3, 5-8, 10, and 13) are the first natural nitrate esters, while the other four (1, 4, 11, and 12) are chlorinated. These compounds are as well the first illudalane sesquiterpenoids to be isolated from the marine environement. Compounds 1, 3, 5, and 8 showeld mild cytotoxicity toward human tumor cell lines.