Flow injection biamperometric determination of captopril

dc.creatorPalomeque, Miriam Edid
dc.creatorFernández Band, Beatriz Susana
dc.date.accessioned2020-02-07T18:36:12Z
dc.date.accessioned2022-10-15T11:56:07Z
dc.date.available2020-02-07T18:36:12Z
dc.date.available2022-10-15T11:56:07Z
dc.date.created2020-02-07T18:36:12Z
dc.date.issued2002-09
dc.identifierPalomeque, Miriam Edid; Fernández Band, Beatriz Susana; Flow injection biamperometric determination of captopril; Elsevier Science; Journal of Pharmaceutical and Biomedical Analysis; 30; 3; 9-2002; 547-552
dc.identifier0731-7085
dc.identifierhttp://hdl.handle.net/11336/96897
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4383301
dc.description.abstractAn automated method to determine captopril (1-[(2S)-3-mercapto-2-methylpropionyl]-L-proline) is proposed. A flow injection manifold based on the indirect biamperometric detection of the captopril by using Fe(III)/Fe(II) as an indicating redox system and a Z-shaped flow-cell configuration, was developed. The calibration curve is linear over the range 0.03-3.6 μg ml-1 of captopril. The relative standard deviation for the determination of 0.76 μg ml-1 of captopril is 0.97% (n=12) and the sample throughput is 69 h-1. This method was applied to the determination of captopril to commercially available pharmaceutical preparations.
dc.languageeng
dc.publisherElsevier Science
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1016/S0731-7085(02)00315-1
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0731708502003151
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectBIAMPEROMETRY
dc.subjectCAPTOPRIL
dc.subjectFLOW INJECTION
dc.titleFlow injection biamperometric determination of captopril
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


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