info:eu-repo/semantics/article
Complete and regioselective deacetylation of peracetylated uridines using a lipase
Fecha
2000-01Registro en:
Iglesias, Luis Emilio; Zinni, Maria Alejandra; Gallo, Mariana; Iribarren, Adolfo Marcelo; Complete and regioselective deacetylation of peracetylated uridines using a lipase; Springer; Biotechnology Letters; 22; 5; 1-2000; 361-365
0141-5492
CONICET Digital
CONICET
Autor
Iglesias, Luis Emilio
Zinni, Maria Alejandra
Gallo, Mariana
Iribarren, Adolfo Marcelo
Resumen
Lipase-catalysed alcoholysis and hydrolysis of 2',3',5-tri-O- acetyluridine (1a) and 2',3',5'-tri-O-acetyl-2'-C-methyluridine (1b) were studied. Conditions for full and regioselective deacetylation of 1a and 1b are shown in the present work. New compound 2',3'-di-O-acetyl-2'-C- methyluridine (3b) was prepared by regioselective lipase-catalysed deacetylation.