Tianeptine influence on plasmatic catecholamine levels and anxiety index in rats under variable chronic stress after early maternal separation

dc.creatorTrujillo, Verónica
dc.creatorMasseroni, Maria Luján
dc.creatorLevin, Gloria Mabel
dc.creatorSuárez Marta Magdalena
dc.date.accessioned2020-05-11T20:16:11Z
dc.date.accessioned2022-10-15T11:01:36Z
dc.date.available2020-05-11T20:16:11Z
dc.date.available2022-10-15T11:01:36Z
dc.date.created2020-05-11T20:16:11Z
dc.date.issued2009-12
dc.identifierTrujillo, Verónica; Masseroni, Maria Luján; Levin, Gloria Mabel; Suárez Marta Magdalena; Tianeptine influence on plasmatic catecholamine levels and anxiety index in rats under variable chronic stress after early maternal separation; Taylor & Francis Ltd; The International Journal Of Neuroscience.; 119; 8; 12-2009; 1210-1227
dc.identifier0020-7454
dc.identifierhttp://hdl.handle.net/11336/104810
dc.identifier1543-5245
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4378530
dc.description.abstractThe aim of this work was to determine the effect of chronic treatment with 5 mg/Kg of tianeptine in male adult Wistar rats separated from the mother as neonates and submitted to variable chronic stress, plasma catecholamines, and anxiety. The plus maze test was performed in order to calculate the anxiety index and catecholamine levels were determined by high-pressure liquid chromatography. Both stress and maternal-separation elevated catecholamine levels without affecting anxiety. In the maternally separated stress group, tianeptine decreased epinephrine. Anxiety was reduced in the maternally separated unstressed tianeptine group. Also, all groups showed a tendency to lower anxiety index.
dc.languageeng
dc.publisherTaylor & Francis Ltd
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://www.tandfonline.com/doi/full/10.1080/00207450802324713
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1080/00207450802324713
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectANXIETY
dc.subjectCATECHOLAMINES
dc.subjectEARLY MATERNAL SEPARATION
dc.subjectPLUS MAZE
dc.subjectTIANEPTINE
dc.subjectVARIABLE CHRONIC STRESS
dc.titleTianeptine influence on plasmatic catecholamine levels and anxiety index in rats under variable chronic stress after early maternal separation
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


Este ítem pertenece a la siguiente institución