info:eu-repo/semantics/article
Redefining Single-Trial Memories in the Honeybee
Fecha
2020-02Registro en:
Villar, María Eugenia; Marchal, Paul; Viola, Haydee Ana Maria; Giurfa, Martín; Redefining Single-Trial Memories in the Honeybee; Elsevier; Cell Reports; 30; 8; 2-2020; 2603-2613.e3
2211-1247
CONICET Digital
CONICET
Autor
Villar, María Eugenia
Marchal, Paul
Viola, Haydee Ana Maria
Giurfa, Martín
Resumen
Research on honeybee memory has led to a widely accepted model in which a single pairing of an odor stimulus with sucrose induces memories that are independent of protein synthesis but is unable to form protein-synthesis-dependent long-term memory (LTM). The latter is said to arise only after three or more pairings of odor and sucrose. Here, we show that this model underestimates the capacity of the bee brain to form LTMs after a unique appetitive experience. Using state-of-the art conditioning setups and individual-based analyses of conditioned responses, we found that protein-synthesis-dependent memories are formed already 4 h after the single conditioning trial and persist even 3 days later. These memories (4 h, 24 h, and 72 h) exhibit different dependencies on transcription and translation processes. Our results thus modify the traditional view of onetrial memories in an insect with a model status for memory research.