info:eu-repo/semantics/article
Cerium ammonium nitrate: A new catalyst for regioselective protection of glycols
Fecha
2004-12Registro en:
Comin, Maria Julieta; Elhalem, Eleonora; Rodriguez, Juan Bautista; Cerium ammonium nitrate: A new catalyst for regioselective protection of glycols; Pergamon-Elsevier Science Ltd; Tetrahedron; 60; 51; 12-2004; 11851-11860
0040-4020
CONICET Digital
CONICET
Autor
Comin, Maria Julieta
Elhalem, Eleonora
Rodriguez, Juan Bautista
Resumen
The regioselective introduction of a methoxymethyl (MOM) group on different type of glycols via an orthoester intermediate was investigated. The novelty presented in this study is the use of ceric ammonium nitrate instead of the previously employed camphorsulfonic acid as catalyst. The monoprotection reaction was revealed to be highly selective when the glycol moiety was in the presence of an ether functionality.