Global phylodynamics of Echovirus 30 revealed differential behavior among viral lineages

dc.creatorLema, Cristina
dc.creatorTorres, Carolina
dc.creatorVan der Sanden, Sabine
dc.creatorCisterna, Daniel
dc.creatorFreire, María Cecilia
dc.creatorGomez, Ricardo Martin
dc.date.accessioned2021-03-31T12:03:07Z
dc.date.accessioned2022-10-15T10:21:43Z
dc.date.available2021-03-31T12:03:07Z
dc.date.available2022-10-15T10:21:43Z
dc.date.created2021-03-31T12:03:07Z
dc.date.issued2019-05
dc.identifierLema, Cristina; Torres, Carolina; Van der Sanden, Sabine; Cisterna, Daniel; Freire, María Cecilia; et al.; Global phylodynamics of Echovirus 30 revealed differential behavior among viral lineages; Academic Press Inc Elsevier Science; Virology; 531; 5-2019; 79-92
dc.identifier0042-6822
dc.identifierhttp://hdl.handle.net/11336/129273
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4375070
dc.description.abstractEchovirus 30 (E30) is an important causative agent of aseptic meningitis worldwide. Despite this, the global and regional dispersion patterns, especially in South America, are still largely unknown. We performed an in-depth analysis of global E30 population dynamics, by using the VP1 sequences of 79 strains isolated in Argentina, between 1998 and 2012, and 856 sequences from GenBank. Furthermore, the 3D pol regions of 329 sequences were analyzed to study potential recombination events. E30 evolution was characterized by co-circulation and continuous replacement of lineages over time, where four lineages appear to circulate at present and another four lineages appear to have stopped circulating. Five lineages showed a global distribution, whereas three other lineages had a more restricted circulation pattern. Strains isolated in South America belong to lineages E and F. Analysis of the 3D pol region of Argentinean strains indicated that recombination events occurred in both lineages.
dc.languageeng
dc.publisherAcademic Press Inc Elsevier Science
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.virol.2019.02.012
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectECHOVIRUS 30
dc.subjectMENINGITIS
dc.subjectPHYLODYNAMICS
dc.subjectPHYLOGEOGRAPHY
dc.subjectRECOMBINATION
dc.titleGlobal phylodynamics of Echovirus 30 revealed differential behavior among viral lineages
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


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