info:eu-repo/semantics/article
Self-sterilizing ormosils surfaces based on photo-synzthesized silver nanoparticles
Fecha
2018-04Registro en:
Gonçalves, Lidiane Patrícia; Miñan, Alejandro Guillermo; Benítez, Guillermo Ignacio; Fernandez Lorenzo, Monica Alicia; Vela, Maria Elena; et al.; Self-sterilizing ormosils surfaces based on photo-synzthesized silver nanoparticles; Elsevier Science; Colloids and Surfaces B: Biointerfaces; 164; 4-2018; 144-154
0927-7765
CONICET Digital
CONICET
Autor
Gonçalves, Lidiane Patrícia
Miñan, Alejandro Guillermo
Benítez, Guillermo Ignacio
Fernandez Lorenzo, Monica Alicia
Vela, Maria Elena
Schilardi, Patricia Laura
Ferreira Neto, Elias Paiva
Noveletto, Júlia Cristina
Correr, Wagner Rafael
Rodrigues Filho, Ubirajara Pereira
Resumen
Medical device-related infections represent a major healthcare complication, resulting in potential risksfor the patient. Antimicrobial materials comprise an attractive strategy against bacterial colonizationand biofilm proliferation. However, in most cases these materials are only bacteriostatic or bactericidal,and consequently they must be used in combination with other antimicrobials in order to reach theeradication condition (no viable microorganisms). In this study, a straightforward and robust antibac-terial coating based on Phosphotungstate Ormosil doped with core-shell (SiO2@TiO2) was developedusing sol-gel process, chemical tempering, and Ag nanoparticle photoassisted synthesis (POrs-CS-Ag).The coating was characterized by X-ray Fluorescence Spectroscopy (XRF), Field Emission ScanningElectron Microscopy (FE-SEM), Atomic Force Microscopy (AFM) and X-ray Photoelectron Microscopy(XPS). The silver free coating displays low antibacterial activity against Staphylococcus aureus and Pseu-domonas aeruginosa, in opposition to the silver loaded ones, which are able to completely eradicate thesestrains. Moreover, the antimicrobial activity of these substrates remains high until three reutilizationcycles, which make them a promising strategy to develop self-sterilizing materials, such as POrs-CS-Ag-impregnated fabric, POrs-CS-Ag coated indwelling metals and polymers, among other materials.