info:eu-repo/semantics/article
Aging behavior of Y-TZP with bioglass addition and its impact on the flexural strength and osteoblastic cell response
Fecha
2020-11Registro en:
Soubelet, Clara Gabriela; Albano, Maria Patricia; Zuardi, Leonardo Raphael; Secco Martorano, Antonio; de Castro Raucci, Larissa Moreira Spinola; et al.; Aging behavior of Y-TZP with bioglass addition and its impact on the flexural strength and osteoblastic cell response; Wiley Blackwell Publishing, Inc; International Journal Of Applied Ceramic Technology; 17; 6; 11-2020; 2792-2806
1546-542X
CONICET Digital
CONICET
Autor
Soubelet, Clara Gabriela
Albano, Maria Patricia
Zuardi, Leonardo Raphael
Secco Martorano, Antonio
de Castro Raucci, Larissa Moreira Spinola
Oliveira, PauloTambasco de
Resumen
Y-TZP containing Ca2P2O7 are promising bioceramics with potential applications in dental implants and dentistry. These ceramics were developed by the introduction of a refractory sol-gel derived CaO-P2O5-SiO2 bioglass into Y-TZP; Ca2P2O7, and ZrSiO4 phases were formed in situ after sintering. The aging process of Y-TZP with different glass additions was studied. The effect of glass addition on the flexural strength and osteoblastic cell response of non-aged and aged Y-TZP was investigated. Y-TZP exhibited the most pronounced tetragonal (t) to monoclinic (m) transformation of zirconia (ZrO2) during aging; the addition of glass contents between 5 and 20 vol% improved the aging resistant of Y-TZP. Y-TZP flexural strength markedly decreased with increasing aging time; in contrast, the ceramics with glass did not alter their flexural strength upon aging. An increase in the Ca2P2O7 content with increasing glass up to 10 vol%, promoted both the cell viability and the osteogenic differentiation of UMR-106 cells on non-aged and aged samples. The high micro-roughness of Y-TZP with 20 vol% glass after aging, limited the proliferation and the osteogenic potential of the cultures. Y-TZP with 10 vol% glass had the best combination of properties in terms of flexural strength and osteoblast cell response.