info:eu-repo/semantics/article
Microbial hydrolysis of acetylated nucleosides
Fecha
2006-07Registro en:
Panero, Julieta; Trelles, Jorge Abel; Rodano, Valeria; Montserrat, Javier Marcelo; Iglesias, Luis Emilio; et al.; Microbial hydrolysis of acetylated nucleosides; Springer; Biotechnology Letters; 28; 14; 7-2006; 1077-1081
0141-5492
CONICET Digital
CONICET
Autor
Panero, Julieta
Trelles, Jorge Abel
Rodano, Valeria
Montserrat, Javier Marcelo
Iglesias, Luis Emilio
Lewkowicz, Elizabeth Sandra
Iribarren, Adolfo Marcelo
Resumen
Enzymatic hydrolysis of acetylated nucleosides using microbial whole cells has been carried out for the first time. Unlike Candida antarctica B lipase-catalysed alcoholysis, none of the tested microorganisms displayed a common deacetylation profile. Depending on the substrate and the biocatalyst used, 5′-selective deprotection or mixtures of mono O-acetylated products were obtained.