info:eu-repo/semantics/article
Fucoidans from the phaeophyta Scytosiphon lomentaria: Chemical analysis and antiviral activity of the galactofucan component
Fecha
2019-04Registro en:
Ponce, Nora Marta Andrea; Flores, Maria Lujan; Pujol, Carlos Alberto; Becerra, Monica Beatriz; Navarro, Diego Alberto; et al.; Fucoidans from the phaeophyta Scytosiphon lomentaria: Chemical analysis and antiviral activity of the galactofucan component; Elsevier; Carbohydrate Research; 478; 4-2019; 18-24
0008-6215
CONICET Digital
CONICET
Autor
Ponce, Nora Marta Andrea
Flores, Maria Lujan
Pujol, Carlos Alberto
Becerra, Monica Beatriz
Navarro, Diego Alberto
Córdoba, Osvaldo León
Damonte, Elsa Beatriz
Stortz, Carlos Arturo
Resumen
The brown seaweed Scytosiphon lomentaria produces moderate amounts of fucoidans. By cetrimide fractionation, typical heavily sulfated galactofucans are obtained, with no major signs of chemical eterogeneity, together with fractions with higher proportions of xylose, mannose and uronic acids. Anyway, fucose is the most important monosaccharide in most of the subfractions of the subsequent extracts. The fucan moieties appear to be mostly as 3-linked α-L-fucopyranosyl units, with several patterns of sulfate and branching. Galactose is mostly 6-linked,whereas mannose appears to be 2-linked, and xylose appears mostly as terminal stubs. Small amounts of 2-Oacetylated fucose units appear. A high and selective antiviral activity against HSV-1 and HSV-2 was determined for the galactofucan fractions whereas the uronofucoidans were inactive.